Tuesday, December 22, 2009

What cause the thyroid cancer?

The human body is like a magic machine, when a certain part of the machine when problems occur, the body will appear to remind us of some small state's attention. However, the daily busy life whether you turn a blind eye to these health warning out? Xiao Bian specifically for the busy home life for you have identified a full range of knowledge, hoping to make your every day off healthy and happy.

The exact cause is difficult to determine the specific affirmative, but epidemiological investigation, experimental cancer research and clinical observation, the incidence of thyroid cancer may be related to the following factors.

(A) X-ray radiation injury in mice of thyroid irradiation can induce thyroid cancer in animals. Results show 131 Ⅰ make changes in the metabolism of thyroid cells, the nucleus deformation, a significant decrease in thyroid hormone synthesis. Radiation can be seen on the one hand caused by the abnormal thyroid cell division, leading to cancer; the other hand, damage to thyroid gland does not produce endocrine hormone, the resulting thyroid stimulating hormone (TSH) secretion can also provoke a large number of cancerous thyroid cells.

Clinically, a lot of facts show that the incidence of thyroid gland and radiation effects. Of particular note is that in the period of infant and child Zengyin proliferation of thymic enlargement, or lymph node samples but to accept the mediastinum or neck radiation therapy for children particularly susceptible to thyroid cancer, it is because children and adolescents vigorous cell proliferation, radiation is an additional stimulus, easy to precipitate the formation of tumors. Adults occurred after neck radiotherapy chances of thyroid cancer is rare.

(B) the excess of iodine and iodide uptake in TSH or iodine deficiency can make the thyroid gland structure and function change. Such as Switzerland endemic goitre endemic areas the incidence of thyroid cancer in Berlin for 2 ‰ higher than 20 times higher than non-epidemic. On the contrary, iodine diet is also easy to induce thyroid cancer, Iceland and Japan are the countries with the highest iodine intake, the thyroid cancer detection rate compared with other countries. This may be related to TSH stimulation of thyroid hyperplasia factors. Experiments show that the long-term TSH stimulation can promote thyroid hyperplasia, the formation of nodules and cancer.

(3) other clinical thyroid disease with thyroid cancer, chronic thyroiditis, nodular goiter, or some toxic goiter to cancer of the reports, but these thyroid disease and thyroid cancer, the relationship between the hard to definitely. With thyroid adenoma, for example, the vast majority of follicular thyroid adenoma, only 2 ~ 5% of the papilloma; such as changes in thyroid cancer by adenoma made, then the majority should be follicular, but the actual More than half of thyroid cancer on the head for the services like cancer, thyroid adenoma speculated that the incidence of cancer is very small.

(D) genetic factors is about 5 ~ 10% of medullary thyroid cancer, a clear family history, and often complicated with pheochromocytoma, etc. Run, speculated that the occurrence of these cancers may be related to chromosome to genetic factors.

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