What is chronic lymphocytic thyroiditis caused by?

The human body is like a magic machine, when a certain part of the machine when problems occur, the body will appear to remind us of some small state's attention. However, the daily busy life whether you turn a blind eye to these health warning out? Xiao Bian specifically for the busy home life for you have identified a full range of knowledge, hoping to make your every day off healthy and happy.

1. The course of disease can be detected in serum from patients with a high titer of anti-thyroid autoantibodies in a variety of components. Such as the thyroid microsomal antibodies, thyroglobulin antibodies, and a portion of patients with thyroid-stimulating blocking antibody (TsBAb) values increased.

2. Evidence of cell-mediated immunity in thyroid tissue from a large number of plasma cells and lymphocytes infiltration and lymphoid follicles. There mother cell (blastcell) formation, migration inhibitory factor, and lymphocyte production of toxins, the patient is sensitized T-lymphocyte activity, the corresponding antigen is mainly thyroid cell membrane.

3. Some patients are also associated with other autoimmune diseases such as pernicious anemia, disseminated scarred red sores, rheumatoid arthritis, Sjogren's syndrome, I diabetes mellitus, chronic active hepatitis. The disease significantly decreased thyroid function during the latter part of clinical practice was myxedema. Inhibition of T-lymphocytes in patients with genetic defects leading to thyroid auto-antibody production. With this disease are still in K cell-mediated immunity, including the release of soluble toxins, including lymphoid cells, leading to thyroid cell damage. In addition to genetic factors and the pathogenesis of autoimmune closely related. Aggregation of this disease have a family phenomenon, and multiple women. Of foreign genes in the HLA study found that Europe and the United States white DBW3, DR5 increased, while the Japanese are DBW53 high frequency.